Reference Pillar / 02 of 04
Purity & Potency
HPLC, mass spectrometry, peptide mapping, and methods for measuring how much active material is in the vial.
Articles
5
Last updated
Sept 2026
Purity and potency ask how much of the target peptide a sample actually contains, and how that figure is measured. This pillar explains what an HPLC area-percent purity result does and does not prove, why identity confirmation by mass spectrometry is a separate question from purity, and how content and net peptide mass differ from the single percentage most buyers focus on. A high number on a certificate means little without the method that produced it.
Articles in this Pillar / 5
- 001HPLC for Peptides: What Every Buyer Should Look Forlabowned editorial
- 002Peptide Purity Testing: What the Percentage Meanslabowned editorial
- 003Mass Spectrometry: Confirming Peptide Identitylabowned editorial
- 004Peptide Mapping: Confirming Sequence Beyond Mass and Puritylabowned editorial
- 005Higher-Order Structure Testing: The Gap Beyond Sequence and Masslabowned editorial