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Reference Pillar / 02 of 04

Purity & Potency

HPLC, mass spectrometry, peptide mapping, and methods for measuring how much active material is in the vial.

Articles

4

Last updated

Aug 2026

Purity and potency ask how much of the target peptide a sample actually contains, and how that figure is measured. This pillar explains what an HPLC area-percent purity result does and does not prove, why identity confirmation by mass spectrometry is a separate question from purity, and how content and net peptide mass differ from the single percentage most buyers focus on. A high number on a certificate means little without the method that produced it.

Articles in this Pillar / 4

  1. 001HPLC for Peptides: What Every Buyer Should Look Forlabowned editorial
  2. 002Peptide Purity Testing: What the Percentage Meanslabowned editorial
  3. 003Mass Spectrometry: Confirming Peptide Identitylabowned editorial
  4. 004Peptide Mapping: Confirming Sequence Beyond Mass and Puritylabowned editorial

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